反应详情

温度

110 °C

A mixture of 7-methoxy-6-nitro-1H-quinolin-2-one (0.13 g) and phosphorus oxychloride (1 mL) was heated at 110° C. for 2 hours. The resulting mixture was then cooled and poured into ice. The solid which formed was collected by filtration and dried under vacuum to afford 0.119 g of 2-chloro-7-methoxy-6-nitro-quinoline as a brown solid.

1. temperatureThe resulting mixture was then cooled
2. additionpoured into ice
3. customThe solid which formed
4. filtrationwas collected by filtration
5. customdried under vacuum