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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1773568Generated: October 26, 2026

Hydrochloric Acid → HCID 58056251, compound

https://huagongshe.com/reaction/1773568

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant6-(3-Hydroxy-propyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl esterHCID 58056314—
CatalystSodium HydroxideHCID 14798—
ProductHCID 58056251HCID 58056251—

Reaction Steps

A mixture of 6-(3-hydroxy-propyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester (5 mg) and an aqueous solution of sodium hydroxide (5 drops) was stirred at room temperature for 16 hours. The reaction mixture was then acidified by addition of an aqueous solution of hydrochloric acid (3 M). The precipitate was collected by filtration to give 6-(3-hydroxy-propyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid. MS=222 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09255110B2
Source datasetuspto-grants-2016_02
ORD IDord-6eecbdc672d54e9b9500e6939deb5dc7
Source noteuspto-grants-2016_02