Trifluoromethanesulfonic acid → HCID 86703999, compound

HRID 1773917Notes

Reaction equation

HRID 1773917 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH2:9][N:10]1[CH:14]=[C:13]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[N:12]=[C:11]1[CH:21]=[O:22].FC(F)(F)S(O)(=O)=O>>[Br:1][C:2]1[C:3]2[CH2:8][CH2:9][N:10]3[C:11](=[N:12][C:13]([C:15]4[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=4)=[CH:14]3)[CH:21]([OH:22])[C:4]=2[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 62406Trifluoromethanesulfonic acidHCID 86704000HCID 86704000, compound

Product 1

HCID 86703999HCID 86703999, compound

Procedure

8-Bromo-2-phenyl-9,10-dihydro-4H-3,10a-diaza-benzo[f]azulen-4-ol is prepared from 1-[2-(2-bromophenyl)ethyl]-4-phenyl-imidazole-2-carbaldehyde (example 231C) analogously to general procedure 123B with trifluoromethanesulfonic acid instead of methanesulfonic acid.

Sources & evidence

ORD record
ord-5779831d5c554d779b211ad4368b18a9
Source dataset
uspto-grants-2016_02
Patent number
US09255101B2

Reaction notes

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