Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Oxybutynin hydrochloride | HCID 91505 | — |
| Solvent | Glycerol | HCID 753 | — |
| Product | Oxybutynin | HCID 4634 | — |
Reaction Steps
The above composition was prepared by mixing the alcohol, oxybutynin chloride and glycerin in a jacketed mixer for about 5 minutes. The KLUCEL® HF was slowly added while continuing to mix. The water and sodium hydroxide solution are added to obtain a pH of about 6. After all ingredients were added, the mixing continued for 1.5 to 3 hours. The temperature of the mixer was maintained between 15-35° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09259388B2 |
|---|
| Source dataset | uspto-grants-2016_02 |
|---|
| ORD ID | ord-9fce53089f38416cbe4fd4d7abf2350e |
|---|
| Source note | uspto-grants-2016_02 |
|---|
