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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1774128Generated: November 1, 2026

Mafenide → HCID 69012110, compound

https://huagongshe.com/reaction/1774128

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMafenideHCID 3998—
ReactantEthanamine, 2,2,2-trifluoro-HCID 9773—
ReactantHCID 69012762HCID 69012762—
ProductHCID 69012110HCID 69012110—

Reaction Steps

6-Bromo-2-methanesulfonyl-quinazolin-4-yl)-(2,2,2-trifluoro-ethyl)-amine was reacted with 4-Aminomethyl-benzenesulfonamide in a manner analogous to 6-Bromo-N2-(4-fluoro-benzyl)-N4-(2,2,2-trifluoro-ethyl)-quinazoline-2,4-diamine as described in Example 49. The product was characterized as follows: MS (m/z) 490 [M+H]+; HPLC Rt=1.90 minutes (Method B).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09259426B2
Source datasetuspto-grants-2016_02
ORD IDord-4d4443ed48b84cd080cb348a053c7988
Source noteuspto-grants-2016_02