2-Methoxyethylamine → HCID 57958803, compound

HRID 1774134Notes

Reaction equation

HRID 1774134 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([NH2:12])[N:6]=[C:5]2[N:13]1[CH:17]=NC=N1.[CH3:18][O:19][CH2:20]CN>>[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([NH2:12])[N:6]=[C:5]2[NH:13][CH2:17][CH2:18][O:19][CH3:20]

Participants

3

Reactant 2

HCID 80182-MethoxyethylamineHCID 57958806HCID 57958806, compound

Product 1

HCID 57958803HCID 57958803, compound

Procedure

The title compound was synthesized by a method analogous to example 23 using 6-Bromo-4-[1,2,4]triazol-1-yl-quinazolin-2-ylamine and 2-methoxyethylamine. The product was characterized as follows: MS (m/z) 297[M+H]+; HPLC Rt=1.05 minutes (Method B).

Sources & evidence

ORD record
ord-ebbfd204c1f74abdb3e52d1ab83cc16b
Source dataset
uspto-grants-2016_02
Patent number
US09259426B2

Reaction notes

Loading…