1-Bromopropane → HCID 178456341, compound

HRID 1774338Notes

Reaction equation

HRID 1774338 reaction equation
[F:1][C:2]([F:19])([F:18])[C:3]1[CH:4]=[C:5]([N:13]2[CH:17]=[CH:16][N:15]=[CH:14]2)[CH:6]=[C:7]([C:9]([F:12])([F:11])[F:10])[CH:8]=1.[Br:20][CH2:21][CH2:22][CH3:23]>C1COCC1>[Br-:20].[F:19][C:2]([F:1])([F:18])[C:3]1[CH:4]=[C:5]([N+:13]2[CH:17]=[CH:16][N:15]([CH2:21][CH2:22][CH3:23])[CH:14]=2)[CH:6]=[C:7]([C:9]([F:10])([F:11])[F:12])[CH:8]=1

Participants

4

Reactant 2

HCID 78401-BromopropaneHCID 86653209HCID 86653209, compound

Product 1

HCID 178456341HCID 178456341, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

According to the general synthesis procedure 3.60 mmol (1.00 g) 1-(3,5-bis(trifluormethyl)phenyl)imidazole and 4.20 mmol (0,530 g, 0.39 ml) 1-bromopropane are dissolved in 5 ml THF and heated for 18 h to 90° C.

Workup

  1. temperatureheated for 18 h to 90° C.

Sources & evidence

ORD record
ord-ba82892854734547bac7b253eb8f5f7c
Source dataset
uspto-grants-2016_02
Patent number
US09260397B2

Reaction notes

Loading…