1-Bromopropane → HCID 178456346, compound

HRID 1774339Notes

Reaction equation

HRID 1774339 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH:14]=[CH:13][N:12]=[CH:11]2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[Br:15][CH2:16][CH2:17][CH3:18]>C1COCC1>[Br-:15].[CH2:16]([N:12]1[CH:13]=[CH:14][N+:10]([C:7]2[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:9][CH:8]=2)=[CH:11]1)[CH2:17][CH3:18]

Participants

4

Reactant 2

HCID 78401-BromopropaneHCID 1231551-(4-Nitrophenyl)-1H-imidazole

Product 1

HCID 178456346HCID 178456346, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

According to the general synthesis procedure, 5.3 mmol (1.00 g) 1-(4-nitrophenyl)imidazole and 6.3 mmol (0.780 g, 0.58 ml) 1-bromopropane are dissolved in 5 ml THF and heated for 17 h to 90° C.

Workup

  1. temperatureheated for 17 h to 90° C.

Sources & evidence

ORD record
ord-dd721afd1c1f451d88d0bc209d5d09e7
Source dataset
uspto-grants-2016_02
Patent number
US09260397B2

Reaction notes

Loading…