1-Bromoheptane → HCID 178443949, compound

HRID 1774345Notes

Reaction equation

HRID 1774345 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH:12]=[CH:11][N:10]=[CH:9]2)=[CH:4][CH:3]=1.[Br:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]>C1COCC1>[Br-:13].[F:1][C:2]1[CH:3]=[CH:4][C:5]([N+:8]2[CH:12]=[CH:11][N:10]([CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[CH:9]=2)=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 123691-BromoheptaneHCID 1408331-(4-Fluorophenyl)imidazole

Product 1

HCID 178443949HCID 178443949, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

According to the general synthesis procedure, 3.09 mmol (0.500 g) 1-(4-fluorophenyl)imidazole and 3.09 mmol (0.509 mg) of 1-bromoheptane are dissolved in 5 ml THF and heated for 12 h to 120° C.

Workup

  1. temperatureheated for 12 h to 120° C.

Sources & evidence

ORD record
ord-b0bc51e3c7f342ab85f45cb19271c243
Source dataset
uspto-grants-2016_02
Patent number
US09260397B2

Reaction notes

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