1-Bromopropane → HCID 178456347, compound

HRID 1774350Notes

Reaction equation

HRID 1774350 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH:13]=[CH:12][N:11]=[CH:10]2)=[CH:5][CH:4]=1.[Br:14][CH2:15][CH2:16][CH3:17]>C1COCC1>[Br-:14].[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N+:9]2[CH:13]=[CH:12][N:11]([CH2:15][CH2:16][CH3:17])[CH:10]=2)=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 78401-BromopropaneHCID 823281-(4-Methoxyphenyl)imidazole

Product 1

HCID 178456347HCID 178456347, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

According to the general synthesis procedure; 4.48 mmol (0.700 g) 1-(4-methoxyphenyl)imidazole and 4.93 mmol (0.606 g, 0.45 ml) 1-bromopropane are dissolved in 5 ml THF and heated for 5 h to 80° C.

Workup

  1. customAccording to the general synthesis procedure
  2. temperatureheated for 5 h to 80° C.

Sources & evidence

ORD record
ord-a577b84c926440088e86f8a004e1f906
Source dataset
uspto-grants-2016_02
Patent number
US09260397B2

Reaction notes

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