1-Bromoheptane → HCID 178443950, compound

HRID 1774355Notes

Reaction equation

HRID 1774355 reaction equation
[F:1][C:2]([F:19])([F:18])[C:3]1[CH:4]=[C:5]([N:13]2[CH:17]=[CH:16][N:15]=[CH:14]2)[CH:6]=[C:7]([C:9]([F:12])([F:11])[F:10])[CH:8]=1.[Br:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]>C1COCC1>[Br-:20].[F:19][C:2]([F:1])([F:18])[C:3]1[CH:4]=[C:5]([N+:13]2[CH:17]=[CH:16][N:15]([CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH:14]=2)[CH:6]=[C:7]([C:9]([F:10])([F:11])[F:12])[CH:8]=1

Participants

4

Reactant 2

HCID 123691-BromoheptaneHCID 86653209HCID 86653209, compound

Product 1

HCID 178443950HCID 178443950, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

According to the general synthesis procedure, 3.60 mmol (1.00 g) 1-(3,5-bis-trifluoromethylphenyl)imidazole and 4.30 mmol (0.770 g, 0.67 ml) 1-bromoheptane are dissolved in 5 ml THF and heated for 18 h to 90° C.

Workup

  1. temperatureheated for 18 h to 90° C.

Sources & evidence

ORD record
ord-d88ac46b3b8848e5a3b9abf69c6806d0
Source dataset
uspto-grants-2016_02
Patent number
US09260397B2

Reaction notes

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