HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1774374Generated: October 31, 2026
HCID 66648453, compound → HCID 59706552, compound
https://huagongshe.com/reaction/1774374
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 66648453 | HCID 66648453 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | HCID 59706552 | HCID 59706552 | 79% |
Reaction Steps
The 3-Benzyl-2-ethyl-2-hydroxysuccinic acid obtained was dissolved in acetic anhydride (35 mL) and stirred at 110° C. for 15 h. The residue obtained by evaporating the acetic anhydride of the reaction mixture under reduced pressure was subjected to silica gel column chromatography (hexane-toluene-ethyl acetate 8:3:1) to give 619 mg of the title compound as oil (yield: 79%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09260375B2 |
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| Source dataset | uspto-grants-2016_02 |
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| ORD ID | ord-0fbc5a679eb84441b8ab91f19049c195 |
|---|
| Source note | uspto-grants-2016_02 |
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