Hydrochloric Acid → HCID 178439349, compound

Participants

Reaction Steps

To a solution of 2-(trans-4-t-butyldimethylsilyloxycyclohexyl)-3-isopropylmaleic anhydride (263 mg, 0.745 mmol) in ethanol (7 mL) was added concentrated. hydrochloric acid (83 mg, 0.84 mmol), and the mixture was left standing at 50° C. for 30 min. The reaction mixture was directly concentrated, and the residue thus obtained was subjected to silica gel column chromatography (hexane-ethyl acetate 1:1) to give 179 mg (quantitative) of the title compound as a solid.

Provenance & Evidence