HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178499981, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 178499980 | HCID 178499980 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178499981 | HCID 178499981 | — |
Reaction Steps
To a solution of dimethyl 2-[4-{2-[2,3-bis(t-butoxycarbonyl)guanidino]ethoxy}benzyl]-3-isopropylmaleate (23.5 mg, 0.0407 mmol) in methanol (470 μL) was added 5 M hydrochloric acid (407 μL) at room temperature, and the mixture was left standing for 4 h. The reaction mixture was concentrated to dryness to give 17.6 mg of the title compound as oil (quantitative).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260375B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-12943eb9cc394e768490aa00986c02c1 |
| Source note | uspto-grants-2016_02 |