HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 86679119, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Thiomorpholine 1,1-dioxide | HCID 6484228 | — |
| Reactant | 3-Bromo-5-(chloromethyl)pyridine | HCID 11701259 | — |
| Product | HCID 86679119 | HCID 86679119 | — |
Reaction Steps
In analogy to the procedure described for the preparation of intermediates A-12 [B], thiomorpholine 1,1-dioxide was reacted with 3-bromo-5-chloromethyl-pyridine (intermediate A-12 [A]) in the presence of NaH to give the title compound as a white solid. MS: 304.9, 307.0 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260408B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-41a0b6acb3c04162b7af603efcd2f232 |
| Source note | uspto-grants-2016_02 |