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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1774751Generated: October 29, 2026

Benzylamine → N-Benzyl-6-chloropyrazin-2-amine

https://huagongshe.com/reaction/1774751

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzylamineHCID 7504—
Reactant2,6-DichloropyrazineHCID 78504—
ReactantDiisopropylethylamineHCID 81531—
ProductN-Benzyl-6-chloropyrazin-2-amineHCID 11708350—

Reaction Steps

In analogy to the procedure described for the preparation of intermediates A-20, benzyl-amine was reacted with 2,6-dichloropyrazine in presence of Hunig's base to give the title compound as a light yellow foam. MS: 220.1 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09260408B2
Source datasetuspto-grants-2016_02
ORD IDord-e232077c32204f0a9f5c58912010860d
Source noteuspto-grants-2016_02