HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropyl iodide → HCID 86679142, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropyl iodide | HCID 6362 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | N-((5-bromopyridin-3-yl)methyl)ethanesulfonamide | HCID 58215658 | — |
| Product | HCID 86679142 | HCID 86679142 | — |
Reaction Steps
In analogy to the procedure described for the preparation of intermediate A-42, ethanesulfonic acid (5-bromo-pyridin-3-ylmethyl)-amide (intermediate A-11) was reacted with 2-iodopropane in presence of NaH (60% in mineral oil) to give the title compound as white solid after purification by reverse phase HPLC on a Gemini-NX column. MS: 323.1 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260408B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-d5166e2636e442cbb4d334ff252b4b0a |
| Source note | uspto-grants-2016_02 |