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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1774822Generated: November 2, 2026

Hydrochloric Acid → HCID 86679172, compound

https://huagongshe.com/reaction/1774822

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 71533569HCID 71533569—
SolventMethanolHCID 887—
ProductHCID 86679172HCID 86679172—

Reaction Steps

In analogy to the procedure described for the preparation of example 42, reaction of (S)-3-[5-(7-fluoro-1-methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-6-yl)-pyridin-3-yloxy]-pyrrolidine-1-carboxylic acid tert-butyl ester (example 52) with hydrogen chloride (in dioxane) in methanol gave the title compound as a yellow solid. MS: 342.1 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09260408B2
Source datasetuspto-grants-2016_02
ORD IDord-b0c5e0b28ce54b658cd564d6ef1f00d5
Source noteuspto-grants-2016_02