HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 89689581, compound → HCID 66596236, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 89689581 | HCID 89689581 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 66596236 | HCID 66596236 | — |
Reaction Steps
A solution of 3-methoxy-5-vinylpyrazin-2-amine (490 mg, 3.08 mmol; see step 1) in 50 mL ethanol was hydrogenated under atmospheric hydrogen pressure using an H-cube employed with a Pd/C-cartridge. Complete conversion were observed and the volatile components were removed using a rotary evaporator to deliver 500 mg (95%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260435B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-0a7ea15c98ec40b9838f37ef6ccb443b |
| Source note | uspto-grants-2016_02 |