HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 178419486, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 1H-Pyrazolo[3,4-c]pyridine | HCID 6451441 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 178419486 | HCID 178419486 | 67% |
Reaction Steps
1H-pyrazolo[3,4-c]pyridine (1 g), bromine (1.33 g), and water (40 mL) were stirred for 1 h. Basification with 20% sodium hydroxide solution, and adjustment to pH 7 by addition of acetic acid, yielded 3-Bromo-1H-pyrazolo[3,4-c]pyridine (1.1 g, 67%). ESI MS m/z=275 (M+1)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260425B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-c6a2eae1594f49609bd45f846296fe88 |
| Source note | uspto-grants-2016_02 |