2-Amino-2',5-dichlorobenzophenone → 2',5-Dichloro-2-(5-oxotetrahydrofuran-2-carbonyl) aminobenzophenone

HRID 1775Notes

Reaction equation

HRID 1775 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][C:3]=1[C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[Cl:12])=[O:5].[O:18]=[C:19]1[O:23][CH:22]([C:24](Cl)=[O:25])[CH2:21][CH2:20]1>>[Cl:12][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=1[C:4](=[O:5])[C:3]1[CH:13]=[C:14]([Cl:17])[CH:15]=[CH:16][C:2]=1[NH:1][C:24]([CH:22]1[CH2:21][CH2:20][C:19](=[O:18])[O:23]1)=[O:25]

Participants

3

Reactant 2

HCID 180692-Amino-2',5-dichlorobenzophenoneHCID 108445405-Oxotetrahydro-2-furancarbonyl chloride

Product 1

HCID 537709252',5-Dichloro-2-(5-oxotetrahydrofuran-2-carbonyl) aminobenzophenone

Procedure

In substantially the same manner as in Example 8 (1), 15 g of 2-amino-2',5-dichlorobenzophenone was allowed to react with 5-oxotetrahydrofuran-2-carbonyl chloride to afford 18.1 g of 2',5-dichloro-2-(5-oxotetrahydrofuran-2-carbonyl) aminobenzophenone, m.p. 170° C.-173° C.

Sources & evidence

ORD record
ord-b0c5b510b8454987be8e23400859a420
Source dataset
uspto-grants-1998_03
Patent number
US05726306

Reaction notes

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