Benzyl Chloride → HCID 89669841, compound

HRID 1775204Notes

Reaction equation

HRID 1775204 reaction equation
CC1(C)CC(=O)C2C3C(C(OC)=O)=CC=CC=3NC=2C1.[CH2:21](Cl)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1.C[N:30]1[C:42]2[CH2:41][CH2:40][CH2:39][C:38]3=[N:43][NH:44][C:45](=[O:46])[C:35]4[C:36]([C:37]=23)=[C:31]1[CH:32]=[CH:33][CH:34]=4>>[CH2:21]([N:30]1[C:42]2[CH2:41][CH2:40][CH2:39][C:38]3=[N:43][NH:44][C:45](=[O:46])[C:35]4[C:36]([C:37]=23)=[C:31]1[CH:32]=[CH:33][CH:34]=4)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

Participants

4

Reactant 3

HCID 7503Benzyl ChlorideHCID 71626391HCID 71626391, compoundHCID 89657302HCID 89657302, compound

Product 1

HCID 89669841HCID 89669841, compound

Procedure

Compound 24 was prepared from methyl 2,2-dimethyl-4-oxo-2,3,4,9-tetrahydro-1H-carbazole-5-carboxylate and benzyl chloride according to the procedures for Compound 22 under appropriate conditions recognized by one of ordinary skill in the art. 1H NMR (DMSO-d6) δ 9.96 (s, 1H), 7.56 (d, 1H, J=8.4 Hz), 7.47 (d, 1H, J=7.8 Hz), 7.11-7.33 (m, 6H), 5.45 (s, 2H), 2.82-2.84 (m, 2H), 2.41-2.43 (m, 2H), and 1.97-2.00 (m, 2H). MS (ESI) m/e [M+1]+ 316.

Sources & evidence

ORD record
ord-9df657969ca9486cb59327176c9e3551
Source dataset
uspto-grants-2016_02
Patent number
US09260440B2

Reaction notes

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