Ethyl trifluoroacetate → HCID 89653236, compound

HRID 1775782Notes

Reaction equation

HRID 1775782 reaction equation
C([O-])(=O)C.[C:5]1([CH2:11][O:12][CH2:13][CH2:14][O:15][CH2:16][CH2:17][O:18][CH2:19][CH2:20][O:21][CH2:22][CH2:23][O:24][CH2:25][CH2:26][O:27][CH2:28][CH2:29][NH3+:30])[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.[F:31][C:32]([F:39])([F:38])[C:33](OCC)=[O:34]>CO>[C:5]1([CH2:11][O:12][CH2:13][CH2:14][O:15][CH2:16][CH2:17][O:18][CH2:19][CH2:20][O:21][CH2:22][CH2:23][O:24][CH2:25][CH2:26][O:27][CH2:28][CH2:29][NH:30][C:33](=[O:34])[C:32]([F:39])([F:38])[F:31])[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

Participants

4

Reactant 2

HCID 9794Ethyl trifluoroacetateHCID 117774129HCID 117774129, compound

Product 1

HCID 89653236HCID 89653236, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of 800 mg of 19-phenyl-3,6,9,12,15,18-hexaoxanonadecylammonium acetate in 5 ml of MeOH was admixed with 75 μl of TEA and 609 μl of ethyl trifluoroacetate, and stirred at RT for 17 h. Solvents and excess reagents were removed, and the residue was filtered on a silica gel column (EE). Yield: 672 mg of colourless oil.

Workup

  1. customSolvents and excess reagents were removed
  2. filtrationthe residue was filtered on a silica gel column (EE)

Sources & evidence

ORD record
ord-56992a10db96414496adb1554a64eab9
Source dataset
uspto-grants-2016_02
Patent number
US09260467B2

Reaction notes

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