HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetraethoxysilane → Hydroxylapatite (Ca5(OH)(PO4)3)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetraethoxysilane | HCID 6517 | — |
| Reactant | Orthosilicic acid | HCID 14942 | — |
| Reactant | Tricalcium Phosphate | HCID 24456 | — |
| Catalyst | Hydrochloric Acid | HCID 313 | — |
| Catalyst | Water | HCID 962 | — |
| Solvent | Water | HCID 962 | — |
| Product | Hydroxylapatite (Ca5(OH)(PO4)3) | HCID 14781 | — |
Reaction Steps
For generating silicic acid, tetraethoxy silane (TEOS, 99%, Sigma) is hydrolyzed by addition of water and hydrochloric acid (10 mmol) as catalyst at 4° C. for 24 hours. The molar ratio of tetraethoxy silane to water is 1:4. This solution serves as the silicate component and is supplied to the collagen suspension that is enriched with calcium phosphate and is mixed intensively. After a few minutes a hydrogel is formed.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09265861B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-b41d55afc9b046dd8a2c117c30be2770 |
| Source note | uspto-grants-2016_02 |