反应详情

A mixture of 2-(benzyloxy)-2-oxoethyl 4-(methylsulfonamidomethyl)-benzoate (0.4 g, 1.060 mmol) and 10% w/w Pd/C (0.056 g, 0.053 mmol) in EtOAc and MeOH 1/1 (30 ml) was shaken under H2 atmosphere (25 psi) for 4 hours. The catalyst was removed by filtration and the filtrate was evaporated to dryness affording 2-(4-(methyl-sulfonamidomethyl)benzoyloxy)acetic acid (0.3 g, 1.044 mmol, 99% yield). The product was used without purification.

1. customThe catalyst was removed by filtration
2. customthe filtrate was evaporated to dryness