Methanesulfonyl chloride → HCID 67025933, compound

Participants

Reaction Steps

Methyl 3-(4-aminophenyl)propanoate (250 mg, 1.39 mmol) was dissolved in DCM (2 ml) and pyridine (500 μl), then methanesulfonyl chloride was added (191 mg, 1.67 mmol), and the mixture was stirred at RT for 2 hours. The reaction was diluted with DCM, and the organic phase was washed with HCl 1N (2×) and brine, dried over Na2SO4 and evaporated under vacuum to give 250 mg of the desired product.

Provenance & Evidence