Hydrochloric Acid → HCID 67973906, compound

Participants

Reaction Steps

A solution of sodium hydroxide 2M (1 mL; 2 mmol) was added to a solution of methyl 2-fluoro-4-(3-fluorobenzyl)benzoate (0.151 g; 0.576 mmol) in ethanol (1 mL). The mixture was stirred at room temperature for 1 hour and the pH of the solution was adjusted to 1 by addition of a solution of 6N hydrochloric acid. The precipitate was collected by filtration and dried under reduced pressure to give 0.141 g (99%) of 2-fluoro-4-(3-fluorobenzyl)benzoic acid as a white solid.

Provenance & Evidence