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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1777684Generated: November 1, 2026

HCID 86699396, compound → HCID 67974414, compound

https://huagongshe.com/reaction/1777684

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86699396HCID 86699396—
SolventTrifluoroacetic acidHCID 6422—
ProductHCID 67974414HCID 6797441460.3%

Reaction Steps

4-(3-Fluorobenzyl)-N-(2-(4,5,6-trifluoro-2-(triethylsilyl)-1H-indol-3-yl)ethyl)benzamide (0.057 g; 0.105 mmol) was dissolved in trifluoroacetic acid (3 mL) and stirred at room temperature for 3 hours. The solution was concentrated under reduced pressure and the crude material was purified by flash chromatography on silica gel (eluent 20 to 100% ethyl acetate in heptane) to afford 0.027 g (60%) of the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266832B2
Source datasetuspto-grants-2016_02
ORD IDord-38c028327fa2471e96b4f7bc9b01b042
Source noteuspto-grants-2016_02