HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86699396, compound → HCID 67974414, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86699396 | HCID 86699396 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 67974414 | HCID 67974414 | 60.3% |
Reaction Steps
4-(3-Fluorobenzyl)-N-(2-(4,5,6-trifluoro-2-(triethylsilyl)-1H-indol-3-yl)ethyl)benzamide (0.057 g; 0.105 mmol) was dissolved in trifluoroacetic acid (3 mL) and stirred at room temperature for 3 hours. The solution was concentrated under reduced pressure and the crude material was purified by flash chromatography on silica gel (eluent 20 to 100% ethyl acetate in heptane) to afford 0.027 g (60%) of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09266832B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-38c028327fa2471e96b4f7bc9b01b042 |
| Source note | uspto-grants-2016_02 |