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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1777685Generated: October 31, 2026

HCID 86699397, compound → HCID 67974538, compound

https://huagongshe.com/reaction/1777685

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86699397HCID 86699397—
SolventTrifluoroacetic acidHCID 6422—
ProductHCID 67974538HCID 6797453819%

Reaction Steps

N-(2-(5-Chloro-7-fluoro-2-(triethylsilyl)-1H-indol-3-yl)ethyl)-4-(3-fluorobenzyl)benzamide (0.102 g; 0.189 mmol) was dissolved in trifluoroacetic acid (3 mL) and stirred at room temperature for 3 hours. The solution was concentrated under reduced pressure and the crude material was purified by flash chromatography on silica gel (eluent 20 to 100% ethyl acetate in heptane) to afford 0.015 g (19%) of the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266832B2
Source datasetuspto-grants-2016_02
ORD IDord-174f1bca7ac742509a58ff0344a8fd7f
Source noteuspto-grants-2016_02