HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Aminopyridine-3,4-dicarbonitrile → N-(4,5-dicyanopyridin-2-yl)-7-(dimethoxymethyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Aminopyridine-3,4-dicarbonitrile | HCID 118036913 | — |
| Reactant | phenyl 7-(dimethoxymethyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate | HCID 118037161 | — |
| Product | N-(4,5-dicyanopyridin-2-yl)-7-(dimethoxymethyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide | HCID 118036695 | — |
Reaction Steps
From intermediate 3 and 6-aminopyridine-3,4-dicarbonitrile, reacted in an analogous manner to the preparation of intermediate 2. (UPLC-MS 1) tR 1.15 min, ESI-MS 379.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09266883B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-a30dc5df28684dddab6ec1b3c6dad100 |
| Source note | uspto-grants-2016_02 |