HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Piperidinol, 1-methyl- → 6-Amino-4-((1-methylpiperidin-4-yl)oxy)nicotinonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Piperidinol, 1-methyl- | HCID 66048 | — |
| Reactant | 6-Amino-4-fluoronicotinonitrile | HCID 118036901 | — |
| Product | 6-Amino-4-((1-methylpiperidin-4-yl)oxy)nicotinonitrile | HCID 118036181 | — |
Reaction Steps
From intermediate 21 and 1-methylpiperidin-4-ol, reacted in an analogous manner to the preparation of intermediate 45. (UPLC-MS 3) tR 0.30 min; ESI-MS 233.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09266883B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-e1177d68ef754be2ae566d2d4ad0a9b5 |
| Source note | uspto-grants-2016_02 |