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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1777901Generated: October 30, 2026

(2S)-1-Methyl-2-pyrrolidinemethanol → HCID 118036524, compound

https://huagongshe.com/reaction/1777901

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S)-1-Methyl-2-pyrrolidinemethanolHCID 643492—
Reactant6-Amino-4-fluoronicotinonitrileHCID 118036901—
ProductHCID 118036524HCID 118036524—

Reaction Steps

From intermediate 21 and (S)-(1-methylpyrrolidin-2-yl)methanol, reacted in an analogous manner to the preparation of intermediate 47. (UPLC-MS 3) tR 0.30 min; ESI-MS 233.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266883B2
Source datasetuspto-grants-2016_02
ORD IDord-a378eda7b4ee46a6955c6aa3a4941ab3
Source noteuspto-grants-2016_02