HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Propanol, 1,1,1-trifluoro-3-methoxy-, (2R)- → HCID 118036516, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Propanol, 1,1,1-trifluoro-3-methoxy-, (2R)- | HCID 86639543 | — |
| Reactant | 6-Amino-4-fluoronicotinonitrile | HCID 118036901 | — |
| Product | HCID 118036516 | HCID 118036516 | — |
Reaction Steps
From intermediate 21 and (R)-1,1,1-trifluoro-3-methoxypropan-2-ol, reacted in an analogous manner to the preparation of intermediate 68. UPLC-MS 3: Rt=0.75 min; MS m/z [M+H]+ 262.1;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09266883B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-a2346496df3d49569bd946bbe0f23782 |
| Source note | uspto-grants-2016_02 |