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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1778027Generated: November 2, 2026

6-Bromo-7-(dimethoxymethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine → 6-Bromo-7-(dimethoxymethyl)-1,2,3,4-tetrahydro-2-methyl-1,8-naphthyridine

https://huagongshe.com/reaction/1778027

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Bromo-7-(dimethoxymethyl)-1,2,3,4-tetrahydro-1,8-naphthyridineHCID 118036297—
Reactant7-(Dimethoxymethyl)-1,2,3,4-tetrahydro-2-methyl-1,8-naphthyridineHCID 118036972—
Product6-Bromo-7-(dimethoxymethyl)-1,2,3,4-tetrahydro-2-methyl-1,8-naphthyridineHCID 118036503—

Reaction Steps

From (racemic) 7-(dimethoxymethyl)-2-methyl-1,2,3,4-tetrahydro-1,8-naphthyridine (intermediate 260), synthesized in an analogous manner to intermediate 12, the title compound was obtained as a light brown oil. (UPLC-MS 6) tR 0.90; ESI-MS 301.1/303.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266883B2
Source datasetuspto-grants-2016_02
ORD IDord-a8cc8a7525b74d46a81c03f3dc968eda
Source noteuspto-grants-2016_02