3-Methoxybenzoic Acid → HCID 118130043, compound

HRID 1778134Notes

Reaction equation

HRID 1778134 reaction equation
[NH2:1][C:2]1[C:11]([C:12]#[C:13][C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([NH2:20])[CH:15]=2)=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][N:3]=1.[CH3:21][O:22][C:23]1[CH:24]=[C:25]([CH:29]=[CH:30][CH:31]=1)[C:26](O)=[O:27]>>[NH2:1][C:2]1[C:11]([C:12]#[C:13][C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([NH:20][C:26](=[O:27])[C:25]3[CH:29]=[CH:30][CH:31]=[C:23]([O:22][CH3:21])[CH:24]=3)[CH:15]=2)=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 114613-Methoxybenzoic AcidHCID 118130098HCID 118130098, compound

Product 1

HCID 118130043HCID 118130043, compound

Procedure

In a manner similar to that described in Example 1, methyl 6-amino-5-((3-aminophenyl)ethynyl)nicotinate and 3-methoxybenzoic acid are converted to the title compound.

Sources & evidence

ORD record
ord-d932c24136594d08bddaaa4f30ce4208
Source dataset
uspto-grants-2016_02
Patent number
US09266869B2

Reaction notes

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