HRID177850

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6344

Dichloromethane

CH2Cl2

HCID6422

Trifluoroacetic acid

C2HF3O2

HCID178446361

未命名化合物

PRODUCTS

产物

HCID178446359

2-[5-[4-[2-amino-3-(2,4-difluorobenzoyl)-6-oxo-1-pyridinyl]-3,5-difluorophenoxy]pentylamino]-4-methylpentanoic acid

C29H31F4N3O5

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-6fd853114d4c41ca898337b637fefb23
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (6/10)

反应SMILES

[Cl:53][CH2:54][Cl:55].[F:46][C:47]([F:48])([F:49])[C:50]([OH:51])=[O:52].[NH2:1][c:2]1[c:3]([C:36]([c:37]2[c:38]([F:44])[cH:39][c:40]([F:43])[cH:41][cH:42]2)=[O:45])[cH:4][cH:5][c:6](=[O:35])[n:7]1-[c:8]1[c:9]([F:34])[cH:10][c:11]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][NH:18][CH:19]([CH2:20][CH:21]([CH3:22])[CH3:23])[C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[cH:31][c:32]1[F:33]>>[NH2:1][c:2]1[c:3]([C:36]([c:37]2[c:38]([F:44])[cH:39][c:40]([F:43])[cH:41][cH:42]2)=[O:45])[cH:4][cH:5][c:6](=[O:35])[n:7]1-[c:8]1[c:9]([F:34])[cH:10][c:11]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][NH:18][CH:19]([CH2:20][CH:21]([CH3:22])[CH3:23])[C:24](=[O:25])[OH:26])[cH:31][c:32]1[F:33]