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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1778540Generated: November 1, 2026

Trifluoroacetic acid → HCID 117697841, compound

https://huagongshe.com/reaction/1778540

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 117697824HCID 117697824—
SolventDichloromethaneHCID 6344—
ProductHCID 117697841HCID 117697841—

Reaction Steps

To a solution of compound 123d (100 mg) in dichloromethane (2.0 mL) was added trifluoroacetic acid (1.0 mL). The reaction mixture was stirred at room temperature for one hour, and concentrated under reduced pressure to give ethyl 2-(6-hydroxy-3-oxa-9-azabicyclo[3.3.1]nonan-7-yl)acetate 123a, which was used directly in next step without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266904B2
Source datasetuspto-grants-2016_02
ORD IDord-75d670500ab64065ae6c5c78d4f18a63
Source noteuspto-grants-2016_02