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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1778677Generated: November 1, 2026

Trifluoroacetic acid → HCID 178493519, compound

https://huagongshe.com/reaction/1778677

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant2-(4-Methylpiperazin-1-yl)pyridine-4-boronic acid, pinacol esterHCID 2769537—
ReactantHCID 178493522HCID 178493522—
ProductHCID 178493519HCID 178493519—

Reaction Steps

This compound was prepared as TFA salt by using procedures analogous to those described for the synthesis of Example 7, Step 3 starting from 6-(2,6-difluoro-3,5-dimethoxyphenyl)-3-iodo-1H-pyrazolo[3,4-d]pyrimidine and 1-methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]piperazine. LCMS (M+H)+=468.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266892B2
Source datasetuspto-grants-2016_02
ORD IDord-15d1ed33567d40fdb708afdc782b75fd
Source noteuspto-grants-2016_02