Bis(pinacolato)diborane → HCID 86722853, compound

HRID 1778756Notes

Reaction equation

HRID 1778756 reaction equation
Br[C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[F:11])[C:7](=[O:12])[N:6]([CH:13]([CH3:15])[CH3:14])[CH2:5]2.CC1(C)C(C)(C)[O:20][B:19](B2OC(C)(C)C(C)(C)O2)[O:18]1>>[F:11][C:10]1[CH:9]=[C:8]2[C:4]([CH2:5][N:6]([CH:13]([CH3:15])[CH3:14])[C:7]2=[O:12])=[CH:3][C:2]=1[B:19]([OH:20])[OH:18]

Participants

3

Reactant 2

HCID 2733548Bis(pinacolato)diboraneHCID 86722852HCID 86722852, compound

Product 1

HCID 86722853HCID 86722853, compound

Procedure

This compound was prepared by using procedures analogous to those described for the synthesis of Example 52, Step 7 starting from 5-bromo-6-fluoro-2-isopropylisoindolin-1-one and 4,4,5,5,4′,4′,5′,5′-octamethyl-[2,2′]bi[[1,3,2]dioxaborolanyl]. LCMS: (M+H)+=238.1.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-0399371578e5414092f4c13feaea84a9
Source dataset
uspto-grants-2016_02
Patent number
US09266892B2

Reaction notes

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