HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylcyclohexylamine → HCID 86681325, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylcyclohexylamine | HCID 7514 | — |
| Reactant | 2-Fluoro-4-iodo-3-methylpyridine | HCID 11776298 | — |
| Product | HCID 86681325 | HCID 86681325 | — |
Reaction Steps
2-Fluoro-4-iodo-3-methylpyridine (700 mg) in N-methylcyclohexanamine (2.2 ml) was heated at 180(C in a Biotage Initiator microwave reactor for 18 hours. The reaction mixture was loaded onto a silica gel cartridge, and was eluted with 0-100% dichloromethane in hexanes to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09266877B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-6a1da3f2da554d4297bcfb53b448577c |
| Source note | uspto-grants-2016_02 |