Hydrochloric Acid → HCID 178479488, compound

HRID 1779367Notes

Reaction equation

HRID 1779367 reaction equation
[C:1]1([C:7]2[CH:16]=[C:15]([C:17]([NH:19][C:20]([NH2:22])=[NH:21])=[O:18])[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:23].C(OCC)C>C(O)C>[ClH:23].[C:1]1([C:7]2[CH:16]=[C:15]([C:17]([NH:19][C:20]([NH2:22])=[NH:21])=[O:18])[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[N:8]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 178513048HCID 178513048, compound

Product 1

HCID 178479488HCID 178479488, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

2-Phenylquinoline-4-carbonylguanidine (1.08 g) formed in Example 1 was suspended in 10 ml of ethanol, and 6 ml (1N) of an ethanol solution of hydrochloric acid were added thereto dropwise at room temperature. Thirty minutes later, ethyl ether was added to the reaction solution, and the crystals were collected by filtration, and dried to obtain 1.12 g of the above-mentioned compound. m.p. 278°-279° C. (decomp.)

Workup

  1. customdropwise at room temperature
  2. filtrationthe crystals were collected by filtration
  3. customdried

Sources & evidence

ORD record
ord-0b235355351e4c64a72c8fd492339021
Source dataset
uspto-grants-1997_05
Patent number
US05627193

Reaction notes

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