Hydroxyamine hydrochloride → HCID 86750792, compound

Participants

Reaction Steps

Heat at reflux for 90 minutes a solution of 0.011 mol of 8H-thieno[2,3-d]pyrrolo[1,2-a]pyrrol-8-one (Preparation 28) and 0.0132 mol of hydroxylamine hydrochloride in 50 ml of pyridine. After cooling and after removal of the pyridine under reduced pressure, the residue is taken up in 150 ml of water and extracted with diethyl ether. The ethereal solution is dried over magnesium sulfate and then concentrated under reduced pressure to yield the title compound in the form of a mixture comprising 70% of the Z form, 30% of the E form.

Provenance & Evidence