Hydrochloric Acid → HCID 22872482, compound

Participants

Reaction Conditions

Reaction Steps

N-[(tert-Butyloxy)carbonyl-3(S)-ethylpyrrolidin-2(S)-ylmethyl]-proline methyl ester 0.081 g, 0.238 mmol) was dissolved in CH3OH (2 mL), cooled to 0° C. and treated with 1N NaOH solution (0.952 mL, 0.952 mmol). After stirring at 23° C. for 3 h, the solution was neutralized with 1N HCl (0.952 mL, 0.952 mmol), concentrated to remove the CH3OH, then lyophilized and the residue used as is.

Provenance & Evidence