Hydrochloric Acid → HCID 19956430, compound

Participants

Reaction Steps

A mixture of 1.26 g (1.84 mmol) of (E)-1,14-di-propyl-1,5,10,14-tetra-BOC-1,5,10,14-tetraazatetradec-7-ene and 19 ml of 3N methanolic hydrochloric acid is stirred for 15 h at room temperature. The reaction mixture is then diluted with 19 ml of diethyl ether, the mixture is filtered, and the filtration residue is washed with diethyl ether. Drying under a high vacuum at 100° C. yields the crystalline title compound (m.p. >260° C.). 1H-NMR (D2O): δ0.95(t,6H); 1.62-1.75(m,4H); 2.05-2.16(m,4H); 3.02(t,4H); 3.11-3.18(m,8H); 3.76(d,4H); 6.04-6.06(m,2H).

Provenance & Evidence