Hydrochloric Acid → HCID 23202221, compound

HRID 1779533Notes

Reaction equation

HRID 1779533 reaction equation
[CH2:1]([N:4](C(OC(C)(C)C)=O)[CH2:5][CH2:6][CH2:7][N:8](C(OC(C)(C)C)=O)[CH2:9]/[CH:10]=[CH:11]/[CH2:12][N:13](C(OC(C)(C)C)=O)[CH2:14][CH2:15][CH2:16][N:17]([CH2:25][CH3:26])C(OC(C)(C)C)=O)[CH:2]=[CH2:3].[ClH:48]>C(OCC)C>[ClH:48].[ClH:48].[ClH:48].[ClH:48].[CH2:1]([NH:4][CH2:5][CH2:6][CH2:7][NH:8][CH2:9]/[CH:10]=[CH:11]/[CH2:12][NH:13][CH2:14][CH2:15][CH2:16][NH:17][CH2:25][CH3:26])[CH:2]=[CH2:3]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19956413HCID 19956413, compound

Product 1

HCID 23202221HCID 23202221, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A mixture of 0.28 g (0.418 mmol) of (E)-1-allyl-14-ethyl-1,5,10,14-tetra-BOC-1,5,10,14-tetraazatetradec-7-ene and 6 ml of 3N methanolic hydrochloric acid is stirred for 6 h at room temperature, and then 10 ml of diethyl ether are added. Working up analogously to Example 1 yields the title compound, m.p. >260° C. 1H-NMR (D2O): δ1.28(t,3H); 2.05-2.17(m,4H); 3.07-3.19(m,10H); 3.69(d,2H); 3.77(d,4H); 5.49-5.55(m,2H); 5.84-5.98(m,1H); 6.04-6.07(m,2H).

Sources & evidence

ORD record
ord-264bf343f8604ed68b17ae8236ecbdcf
Source dataset
uspto-grants-1997_05
Patent number
US05627215

Reaction notes

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