Hydrochloric Acid → HCID 19956400, compound

HRID 1779535Notes

Reaction equation

HRID 1779535 reaction equation
[CH2:1]([N:3](C(OC(C)(C)C)=O)[CH2:4][CH2:5][CH2:6][N:7](C(OC(C)(C)C)=O)[CH2:8]/[CH:9]=[CH:10]/[CH2:11][N:12](C(OC(C)(C)C)=O)[CH2:13][CH2:14][CH2:15][N:16](C)[C:17](OC(C)(C)C)=O)[CH3:2].[ClH:46]>C(OCC)C>[ClH:46].[ClH:46].[ClH:46].[ClH:46].[CH2:1]([NH:3][CH2:4][CH2:5][CH2:6][NH:7][CH2:8]/[CH:9]=[CH:10]/[CH2:11][NH:12][CH2:13][CH2:14][CH2:15][NH:16][CH3:17])[CH3:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19956386HCID 19956386, compound

Product 1

HCID 19956400HCID 19956400, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A mixture of 0.32 g (0.498 mmol) of (E)-1-ethyl-14-methyl-1,5,10,14-tetra-BOC-1,5,10,14-tetraazatetradec-7-ene and 6 ml of 3N methanolic hydrochloric acid is stirred for 15 h at room temperature, and then 10 ml of diethyl ether are added. Working up analogously to Example 1 yields the title compound, m.p. >260° C. 1H-NMR (D2O): δ1.28(t,3H); 2.03-2.17(m,4H); 2.74(s,3H); 3.07-3.19(m,10H); 3.77(d,4H); 6.04-6.07(m,2H).

Sources & evidence

ORD record
ord-2733dee3f7a045bfac566f5c122e2306
Source dataset
uspto-grants-1997_05
Patent number
US05627215

Reaction notes

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