Hydrochloric Acid → HCID 19956432, compound

HRID 1779537Notes

Reaction equation

HRID 1779537 reaction equation
[CH2:1]([N:5](C(OC(C)(C)C)=O)[CH2:6][CH2:7][CH2:8][N:9](C(OC(C)(C)C)=O)[CH2:10]/[CH:11]=[CH:12]/[CH2:13][N:14](C(OC(C)(C)C)=O)[CH2:15][CH2:16][CH2:17][N:18]([CH2:26][CH3:27])C(OC(C)(C)C)=O)[CH2:2][CH2:3][CH3:4].[ClH:49]>C(OCC)C>[ClH:49].[ClH:49].[ClH:49].[ClH:49].[CH2:1]([NH:5][CH2:6][CH2:7][CH2:8][NH:9][CH2:10]/[CH:11]=[CH:12]/[CH2:13][NH:14][CH2:15][CH2:16][CH2:17][NH:18][CH2:26][CH3:27])[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19956404HCID 19956404, compound

Product 1

HCID 19956432HCID 19956432, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A mixture of 0.3 g (0.438 mmol) of (E)-1-butyl-14-ethyl-1,5,10,14-tetra-BOC-1,5,10,14-tetraazatetradec-7-ene and 6 ml of 3N methanolic hydrochloric acid is stirred for 15 h at room temperature, and then 10 ml of diethyl ether are added. Working up analogously to Example 1 yields the title compound, m.p. >260° C. 1H-NMR (D2O): δ0.91 (t,3H); 1.27(t, 3H); 1.32-1.45(m,2H); 2.05-2.16(m,4H); 3.03-3.19(m,12H); 3.77(d,4H); 6.04-6.07(m,2H).

Sources & evidence

ORD record
ord-ad4b1490202c4a6fb4166f6cd727c01a
Source dataset
uspto-grants-1997_05
Patent number
US05627215

Reaction notes

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