Hydrochloric Acid → HCID 19956382, compound

HRID 1779539Notes

Reaction equation

HRID 1779539 reaction equation
[CH2:1]([N:3](C(OC(C)(C)C)=O)[CH2:4][CH2:5][CH2:6][N:7](C(OC(C)(C)C)=O)[CH2:8]/[CH:9]=[CH:10]/[CH2:11][N:12](C(OC(C)(C)C)=O)[CH2:13][CH2:14][CH2:15][N:16]([CH2:24][CH2:25][CH3:26])C(OC(C)(C)C)=O)[CH3:2].[ClH:48]>C(OCC)C>[ClH:48].[ClH:48].[ClH:48].[ClH:48].[CH2:1]([NH:3][CH2:4][CH2:5][CH2:6][NH:7][CH2:8]/[CH:9]=[CH:10]/[CH2:11][NH:12][CH2:13][CH2:14][CH2:15][NH:16][CH2:24][CH2:25][CH3:26])[CH3:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19956414HCID 19956414, compound

Product 1

HCID 19956382HCID 19956382, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A mixture of 0.5 g (0.745 mmol) of (E)-1-ethyl-14-propyl-1,5,10,14-tetra-BOC-1,5,10,14-tetraazatetradec-7-ene and 10 ml of 3N methanolic hydrochloric acid is stirred for 15 h at room temperature, and then 20 ml of diethyl ether are added. Working up analogously to Example 1 yields the title compound, m.p. >260° C. 1H-NMR (D2O): δ0.96(t,3H); 1.28(t,3H); 1.63-1.76(m,2H); 2.05-2.16(m,4H); 2.97-3.18(m,12H); 3.77(d,4H); 6.05-6.07(m,2H).

Sources & evidence

ORD record
ord-67407459c9f04a6ea533ed280f27dfe2
Source dataset
uspto-grants-1997_05
Patent number
US05627215

Reaction notes

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