Water → HCID 178507419, compound

HRID 1779987Notes

Reaction equation

HRID 1779987 reaction equation
[NH:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[CH:8][CH:7]=2)[N:3]=[N:2]1.O>C(O)(=O)C.[Pd].[C]>[NH:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[CH:10][C:9]([NH2:12])=[CH:8][CH:7]=2)[N:3]=[N:2]1

Participants

5

Reactant 2

HCID 962WaterHCID 178526530HCID 178526530, compound

Product 1

HCID 178507419HCID 178507419, compoundYield 71%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 176Acetic AcidSolvent

Procedure

A 5 g portion of 4-triazolylnitrobenzene dissolved in 20 ml of acetic acid was mixed with 0.3 g of 10% Pd-carbon and subjected to hydrogenation under a hydrogen pressure of 3 kg/cm2. The reaction solution was poured into water and extracted with chloroform. The resulting organic layer was washed with sodium bicarbonate aqueous solution and water in that order and dried, and the solvent was removed by evaporation under a reduced pressure to obtain 3 g of 4-triazolylaniline with a yield of 71%.

Workup

  1. extractionextracted with chloroform
  2. washThe resulting organic layer was washed with sodium bicarbonate aqueous solution and water in that order
  3. customdried
  4. customthe solvent was removed by evaporation under a reduced pressure

Sources & evidence

ORD record
ord-eb4a7f2b49cb44b6b8e8b644a41065b0
Source dataset
uspto-grants-1997_05
Patent number
US05629332

Reaction notes

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