Ammonia → HCID 178479083, compound

Participants

Reaction Steps

A solution of 15 mg (0.078 mmol) of 2-imino-5-(S)-acetyloxymethylpyrrolidine hydrochloride prepared in example 7 in 3 mL of methanol was saturated with NH3 and the solution was stirred for 3 h. The reaction mixture was concentrated and the residual solid was suspended in Et2O-EtOAc, filtered and washed with Et2O and dried to isolate 6 mg of the title compound.

Provenance & Evidence